Acute Coronary Syndrome (ACS) is an umbrella term for a group of clinical symptoms that can occur when the blood supplied to the heart muscle is suddenly blocked. ACS is the most common cause of morbidity and mortality in the US, with approximately 1.5 million hospital discharges in the US involving patients with ACS, and accounts for half of all deaths due to cardiovascular disease. The economic impact of ACS is also very high, costing Americans more than $150 billion annually.


ACS includes:
1) unstable angina
2) non-ST-segment elevation myocardial infarction (NSTEMI)
3) ST-segment elevation myocardial infarction (STEMI). Approximately 80% of ACS cases are either unstable angina or NSTEMI, and 20% are STEMI.


References
  • Roger VL, Go AS, Lloyd-Jones DM, et al. Heart disease and stroke statistics, 2012 update: a report from the American Heart Association. Circulation. 2012;125(1):e2-e220
  • Mozaffarian D, Benjamin EJ, Go AS, et al. Heart disease and stroke statistics, 2015 update: a report from the American Heart Association. Circulation. 2015;131:e29-e322



    Treatment of ACS